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Karman Line digital therapeutics



Fatigue is one of the most commonly reported complaints after acquired brain injury. It affects about half of all patients to a greater or lesser extent and it is therefore assumed that fatigue is primarily caused by the brain injury itself.

An explanation for this can be found in the coping hypothesis (Van Zomeren et al. 1984), which states that attention problems require the patient to put in more effort to perform the same as before the brain injury. Evidence for this explanation was found in imaging studies which concluded that activation in the brains of these patients was more scattered during attention tasks than in healthy controls. Suggesting that patients have to compensate for their processing difficulties through activation of additional brain areas. This could subsequently cause and/ or increase fatigue, which has a major impact on all areas of life: work, social relationships, hobbies and so on.



A basic premise of this treatment protocol is that fatigue is primarily caused by the brain itself. The aim of the treatment is not to restore energy levels to premorbid levels, but to distribute available energy more efficiently throughout the day and teach patients how to cope with existing fatigue. The Energy training encompasses an adapted version of the proven successful Cognitive and Graded Activity Training (COGRAT) for individuals who experience fatigue (Zedlitz et al. 2012) and consists of an Energy Game and Energy Tool.



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